Condition: Rheumatoid Arthritis (RA) · Psoriatic Arthritis (PsA) · Axial Spondyloarthritis (AxSpA) · Sponsor: Sint Maartenskliniek
The goal of this clinical trial is to assess the effectiveness of a disease activity guided dose reduction strategy of Janus kinase inhibitor (JAKi) compared to disease activity guided JAKi continuation in patients with rheumatoid arthritis (RA), psoriatic arthritis (PsA) and axial spondyloarthritis (axSpA) who are in a state of low disease activity or remission while on JAKi. The main question it aims to answer is: Is a disease activity guided dose reduction strategy for JAKi not inferior in terms of efficacy compared to disease activity guided JAKi continuation in patients with RA/PsA/axSpA that are currently in a low disease activity/remission state? Researchers will compare a disease activity guided dose reduction strategy for JAKi to disease activity guided JAKi continuation in patients with RA/PsA/axSpA that are currently in a low disease activity/remission state to see if a disease activity guided dose reduction strategy for JAKi is not inferior in terms of efficacy compared to disease activity guided JAKi continuation. Participants will: * Follow a JAKi dose reduction strategy or will continue using JAKi in the same dose * Study (telemonitoring) visits are planned every 3 months * At every visit, patients are asked to complete patient-reported outcomes that assess daily functioning, health-related quality of life, pain, fatigue, productivity loss, medical consumption and medication adherence.
This description comes directly from the study's public registry record.
Contact details are listed per location below or on the registry record.
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| Sint Maartenskliniek Nijmegen | Nijmegen, Gelderland, Netherlands | Recruiting |
| Maastricht UMC+ | Maastricht, Limburg, Netherlands | Not Yet Recruiting |
| Elisabeth-TweeSteden Ziekenhuis Tilburg | Tilburg, North Brabant, Netherlands | Not Yet Recruiting |
| Medisch Spectrum Twente | Enschede, Overijssel, Netherlands | Not Yet Recruiting |
| Isala Zwolle | Zwolle, Overijssel, Netherlands | Not Yet Recruiting |
| Erasmus MC | Rotterdam, South Holland, Netherlands | Not Yet Recruiting |
| Maasstad ziekenhuis | Rotterdam, South Holland, Netherlands | Not Yet Recruiting |
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Source record: clinicaltrials.gov/study/NCT07160231