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Study identifier: NCT07158710 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase I Study of HSK42360 in Malignant Brain Tumors With BRAF V600 Mutation

Condition: Malignant Brain Tumors  ·  Sponsor: Haisco Pharmaceutical Group Co., Ltd.

PhasePhase 1
Planned participants159
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase I, open-label, dose-escalation and expansion study to evaluate the safety, tolerability, PK of HSK42360 when given orally in pediatric patients with active BRAF V600 mutation recurrent malignant brain tumors.

This description comes directly from the study's public registry record.

Talk to the study team

Contact details are listed per location below or on the registry record.

Always discuss trial participation with your own doctor first.

Locations (6)

Xuanwu Hospital Capital Medical UniversityBeijing, Beijing Municipality, ChinaRecruiting
Department of Neuro-oncology, Cancer Center, Beijing Tiantan Hospital, Capital Medical University,Beijing, ChinaBeijing, Beijing Municipality, ChinaRecruiting
The first affiliated hospital of fujian medical universityFuzhou, Fujian, ChinaRecruiting
Zhujiang Hospital of Southern Medical UniversityGuangzhou, Guangdong, ChinaRecruiting
The Third Bethune Hospital of Jilin UniversityChangchun, Jilin, ChinaRecruiting
Fudan University Affiliated Huashan HospitalShanghai, Shanghai Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07158710