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Study identifier: NCT07154563 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Rapid Assessment of Sentinel Lymph Node Metastasis Status Using a Pan-CK-targeting NIR-II Fluorescent Probe in Breast Cancer

Condition: Breast Cancer Metastatic · Sentinel Lymph Node · Sentinel Lymph Node Biopsy (SLNB)  ·  Sponsor: Yunnan Cancer Hospital

PhaseN/A
Planned participants60
Who can joinFemale, 18 Years to 75 Years
Healthy volunteersNo

About this study

Breast malignant tumors are a serious threat to women's health, and the current treatment for breast malignant tumors is still dominated by surgery, but the problems faced by patients after surgery such as edema and tumor recurrence are still relatively common, and the high recurrence rate and the occurrence of postoperative complications are closely related to the removal of metastatic lymph nodes during surgery. Therefore, accurate assessment of sentinel lymph node (SLN) metastases is essential to determine the extent of axillary lymph node dissection (ALND) and minimize complications. In this study, we developed a new technique that can rapidly distinguish between metastatic lymph nodes and normal sentinel lymph nodes (SLNs) in breast cancer patients. Briefly, fresh tissue is incubated with the probe and imaged immediately after intraoperative sentinel lymph node resection to identify the metastatic status of SLN. The accuracy of fluorescence imaging is confirmed by pathological diagnosis.

This description comes directly from the study's public registry record.

Talk to the study team

Junhong Chen, Postgraduate  ·  86+17782287838  ·  1145644908@qq.com

Weiling Chen, Doctor  ·  86+13646039812  ·  913208146@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Yunnan Cancer Hospital, Kunming, Yunnan 650118Kunming, Yunnan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07154563