Condition: Acute Lymphoblastic Leukemia (ALL) Philadelphia Chromosome-positive (Ph+) · Childhood Leukemia, Acute Lymphoblastic · Sponsor: Institute of Hematology & Blood Diseases Hospital, China
This prospective clinical trial evaluates the effectiveness and safety of "chemotherapy-light" regimen incorporating the third-generation TKI olverembatinib, the bi-specific CD3/CD19 T cell engager blinatumomab, and the BCL-2 selective inhibitor venetoclax for newly diagnosed pediatric/adolescent patients with Ph+ ALL. The CCCG-Ph+ B-ALL-2025 protocol will be modified as following compared to the CCCG-ALL-2020 protocol
This description comes directly from the study's public registry record.
Jingliao Zhang, MD · +86 22 23909196 · zhangjingliao@ihcams.ac.cn
Xiaofan Zhu, MD · + 86 22 23909001 · xfzhu@ihcams.ac.cn
Always discuss trial participation with your own doctor first.
| Anhui Medical University Second Affiliated Hospita | Hefei, Anhui, China | Not Yet Recruiting |
| Chongqing Medical University Affiliated Children's Hospital | Chongqing, Chongqing Municipality, China | Not Yet Recruiting |
| Fujian Medical University Union Hospital | Fuzhou, Fujian, China | Not Yet Recruiting |
| Guangzhou Women and Children's Medical Center | Guangzhou, Guangdong, China | Not Yet Recruiting |
| Nanfang Hospital, Southern Medical University | Guangzhou, Guangdong, China | Not Yet Recruiting |
| The First Affiliated Hospital, Sun Yat-sen University | Guangzhou, Guangdong, China | Not Yet Recruiting |
| The Affiliated Hospital of Guizhou Medical University | Guiyang, Guizhou, China | Not Yet Recruiting |
| Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology | Wuhan, Hubei, China | Not Yet Recruiting |
| Union Hospital of Tongji Medical College, Huazhong University of Science and Technology | Wuhan, Hubei, China | Not Yet Recruiting |
| Wuhan Children's Hospital | Wuhan, Hubei, China | Not Yet Recruiting |
| Hunan Children's Hospital | Changsha, Hunan, China | Not Yet Recruiting |
| The Third Xiangya Hospital of the Central South University | Changsha, Hunan, China | Not Yet Recruiting |
+ 12 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07152041