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Study identifier: NCT07148128 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Phase 1/2a Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of WEF-001 as Monotherapy in Advanced KRAS-Mutant Solid Tumours.

Condition: Advanced or Metastatic KRAS-mutant Tumor in Pancreatic Adenocarcinoma · Advanced or Metastatic KRAS-mutant Tumor in Colorectal Cancer · Advanced or Metastatic KRAS-mutant Tumor in Non Small Cell Lung Cancer  ·  Sponsor: Auricula Biosciences Inc.

PhasePhase 1/Phase 2
Planned participants110
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a study designed to assess the safety, tolerability, pharmacokinetics and preliminary efficacy of WEF-001 as monotherapy in patients with Advanced KRAS-mutant solid tumours.

This description comes directly from the study's public registry record.

Talk to the study team

Michele Finn, MSc  ·  1-438-884-9551  ·  inquiries@auriculabiosciences.com

Always discuss trial participation with your own doctor first.

Locations (4)

NEXT Oncology DallasDallas, Texas, United StatesRecruiting
Next Oncology, San AntonioSan Antonio, Texas, United StatesRecruiting
Princess Margareth Cancer CenterToronto, Ontario, CanadaRecruiting
Oxford University HospitalHeadington, Oxford, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT07148128