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Study identifier: NCT07146646 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Trifluridine/Tipiracil + Oxaliplatin in Participants With Advanced or Metastatic Biliary Tract Cancer

Condition: Biliary Tract Cancer · Biliary Tract Neoplasms · Cholangiocarcinoma  ·  Sponsor: Case Comprehensive Cancer Center

PhasePhase 2
Planned participants27
Who can joinAll sexes, 19 Years to no upper limit
Healthy volunteersNo

About this study

Participants are eligible for this study who were treated for advanced biliary tract cancer (BTC) but the treatment either did not make the cancer better or is no longer working. The treatment for patients whose advanced BTC either did not make the cancer better or is no longer working is a combination of chemotherapy drugs called FOLFOX which consists of fluorouracil and oxaliplatin. Studies have shown that other treatments may work better to treat advanced BTC. In this study, investigators want to see if treating patients with the drug combination of trifluridine/tipiracil (FTD/TPI) and another drug called oxaliplatin works better than FOLFOX for advanced BTC as second-line therapy. FTD/TPI are pills that are taken by mouth, whereas oxaliplatin is given intravenously (by IV).

This description comes directly from the study's public registry record.

Talk to the study team

Madison Conces, MD  ·  216-844-3951  ·  Madison.Conces@UHhospitals.org

Always discuss trial participation with your own doctor first.

Locations (2)

University Hospitals Seidman Cancer Center, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesRecruiting
Cleveland Clinic Taussig Cancer Center, Case Comprehensive Cancer CenterCleveland, Ohio, United StatesNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07146646