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Study identifier: NCT07145450 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC

Condition: PDAC  ·  Sponsor: Anocca AB

PhasePhase 1/Phase 2
Planned participants96
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label, multi-centre, single-arm Phase 1/2 clinical trial of the safety, expansion, persistence and clinical activity of a set of engineered autologous T cells products each capable of recognizing a specific combination mutated KRAS and HLA, activating the T cells and exerting anti- tumour activity in patients with metastatic or locally advanced PDAC.

This description comes directly from the study's public registry record.

Talk to the study team

Amu Wang  ·  +46703784946  ·  amu.wang@anocca.com

Anocca AB  ·  +46841080701  ·  clinical.trials@anocca.com

Always discuss trial participation with your own doctor first.

Locations (10)

Herlev and Gentofte University HospitalCopenhagen, DenmarkRecruiting
Charité Universitätsmedizin BerlinBerlin, GermanyRecruiting
Technische Universitaet Dresden - Universitaetsklinikum Carl Gustav CarusDresden, GermanyRecruiting
Universitaetsklinikum HeidelbergHeidelberg, GermanyRecruiting
Universitaetsklinikum Leipzig - Universitaeren Krebszentrum (UCCL)Leipzig, GermanyNot Yet Recruiting
Ludwig-Maximilians-Universitaet Muenchen (LMU) Klinikum der Universitaet Muenchen - Campus Grosshadern - Medizinische Klinik und Poliklinik IIIMünchen, GermanyNot Yet Recruiting
University Hospital and Faculty of Medicine Eberhard Karls University TübingenTübingen, GermanyRecruiting
Amsterdam UMC - VU Medical CenterAmsterdam, NetherlandsRecruiting
Radboud University Medical CenterNijmegen, NetherlandsRecruiting
Karolinska University HospitalStockholm, SwedenRecruiting

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Source record: clinicaltrials.gov/study/NCT07145450