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Study identifier: NCT07145112 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma

Condition: Glioblastoma  ·  Sponsor: University of California, Davis

PhasePhase 1
Planned participants20
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a phase 1 study evaluating the safety and feasibility of laser interstitial thermal therapy (LITT) followed by lomustine (CCNU) for recurrent glioblastoma in adults. The primary aim is to evaluate the safety of the combination of LITT plus lomustine based on the assessment of treatment-related adverse events and the feasibility of completing LITT + lomustine in the proposed timeframe. The secondary aim is to assess overall survival for up to 2 years after the first dose of lomustine.

This description comes directly from the study's public registry record.

Talk to the study team

Orwa Aboud, MD, PhD  ·  916-734-3772  ·  oaboud@health.ucdavis.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of California Davis Comprehensive Cancer CenterSacramento, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07145112