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Study identifier: NCT07144826 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effects of a Probiotic Intervention on the Gut and Vaginal Microbiome in Patients With Advanced or Recurrent Ovarian Cancer Undergoing Treatment With Platinum Chemotherapy

Condition: Advanced Ovarian Carcinoma · Recurrent Ovarian Carcinoma · Stage II Ovarian Cancer AJCC v8  ·  Sponsor: Ohio State University Comprehensive Cancer Center

PhaseEARLY_Phase 1
Planned participants161
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial evaluates the effects a probiotic intervention has on the gut and vaginal microbiome in patients undergoing chemotherapy for ovarian cancer that may have spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) or that has come back after a period of improvement (recurrent). Gut health is also known as the gut microbiome. The microbiome includes all of the bacteria and organisms naturally found in the digestive tract. Probiotics are dietary supplements containing live microorganisms that may help keep the gastrointestinal tract healthy. A probiotic intervention during platinum chemotherapy in ovarian cancer patients may impact the gut and vaginal microbiota, quality of life, symptoms, and oncologic outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

The Ohio State University Comprehensive Cancer Center  ·  800-293-5066  ·  OSUCCCClinicaltrials@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Ohio State University Comprehensive Cancer CenterColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07144826