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Study identifier: NCT07144111 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Evaluate the Effect of Moderate or Severe Hepatic Impairment on the Pharmacokinetics (PK) of Inavolisib

Condition: Hepatic Impairment  ·  Sponsor: Genentech, Inc.

PhasePhase 1
Planned participants32
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersYes

About this study

This open-label study will evaluate the effect on the pharmacokinetics (PK), safety, and tolerability of a single oral dose of inavolisib in participants with moderate or severe hepatic impairment compared with demographically matched healthy participants with normal hepatic function.

This description comes directly from the study's public registry record.

Talk to the study team

Reference Study ID Number: GP45942 https://forpatients.roche.com/ No attachments to email below.  ·  888-662-6728 (U.S. and Canada)  ·  global-roche-genentech-trials@gene.com

Fastest response: use the inquiry form. https://www.gene.com/contact-us/submit-medical-inquiry

Always discuss trial participation with your own doctor first.

Locations (4)

Orange County Research CenterLake Forest, California, United StatesRecruiting
Orlando Clinical Research CenterOrlando, Florida, United StatesRecruiting
The Texas Liver Institute, Inc.San Antonio, Texas, United StatesRecruiting
Pinnacle Clinical Research - San AntonioSan Antonio, Texas, United StatesRecruiting

Follow this study

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Source record: clinicaltrials.gov/study/NCT07144111