Condition: Venous Thromboembolism (VTE) · Exercise Therapy · Quality of Life (QOL) · Sponsor: Insel Gruppe AG, University Hospital Bern
Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with anticoagulation (blood thinners). The randomized RehabPE trial investigates whether an early, structured rehabilitation program with physical training and patient education can prevent such long-term effects. The study includes hospitalized patients with acute symptomatic PE who are at increased risk of impaired quality of life three months after diagnosis. After informed consent, patients are randomly assigned to one of two groups: one receives an early 6-8-week, center-based rehabilitation program; the other receives standard follow-up care without rehabilitation. The intervention group completes 16-18 outpatient sessions of endurance and strength training, along with two education sessions covering the condition, treatment, and symptom management. Over 180 days, changes in quality of life, physical exercise capacity, breathlessness, and psychological symptoms, and the time to return to work / usual daily activities will be monitored and compared between groups.
This description comes directly from the study's public registry record.
Tobias Tritschler, Prof. Dr. med., MSc · +41 (0)31 632 01 46 · tobias.tritschler@insel.ch
Always discuss trial participation with your own doctor first.
| Cantonal Hospital Aarau | Aarau, Switzerland | Recruiting |
| Cantonal Hospital Baden | Baden, Switzerland | Recruiting |
| Inselspital, Bern University Hospital | Bern, Switzerland | Recruiting |
| Geneva University Hospitals | Geneva, Switzerland | Recruiting |
| Lausanne University Hospital | Lausanne, Switzerland | Recruiting |
| University Hospital Zürich | Zurich, Switzerland | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07143539