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Study identifier: NCT07142252 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus

Condition: Type 1 Diabetes Mellitus  ·  Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

PhasePhase 2
Planned participants66
Who can joinAll sexes, 8 Years to 45 Years
Healthy volunteersNo

About this study

This Phase 2 study is a 2-arm, multi-center, double-masked (masking of the participant, care provider and investigator), placebo-controlled, 2:1 randomized trial design in new onset T1D participants (within 100 days of diagnosis). Participants will be administered rezpegaldesleukin/placebo once every 14 days over 26 weeks with an additional 6-month follow-up period.

This description comes directly from the study's public registry record.

Talk to the study team

Jessica Conaty  ·  813-396-9234  ·  Jessica.Conaty@epi.usf.edu

Always discuss trial participation with your own doctor first.

Locations (10)

Barbara Davis Center for DiabetesAurora, Colorado, United StatesRecruiting
University of FloridaGainesville, Florida, United StatesRecruiting
University of MiamiMiami, Florida, United StatesRecruiting
Joslin Diabetes CenterBoston, Massachusetts, United StatesRecruiting
Columbia UniversityNew York, New York, United StatesRecruiting
University of PittsburghPittsburgh, Pennsylvania, United StatesRecruiting
Vanderbilt UniversityNashville, Tennessee, United StatesRecruiting
University of UtahSalt Lake City, Utah, United StatesRecruiting
Benaroya Research InstituteSeattle, Washington, United StatesRecruiting
University of British ColumbiaVancouver, British Columbia, CanadaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07142252