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Study identifier: NCT07142122 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Safety Comparison of Total Laparoscopic Proximal Gastrectomy With or Without Preservation of the Celiac Branch of the Vagus Nerve for Early Upper Gastric Cancer: A Randomized Controlled Clinical Trial

Condition: Gastric Cancer  ·  Sponsor: Fujian Cancer Hospital

PhaseNA
Planned participants76
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This prospective, single-center, randomized, controlled, non-inferiority clinical trial aims to compare the safety and postoperative quality of life of early upper gastric cancer patients undergoing total laparoscopic proximal gastrectomy (TLPG) with preservation of both the hepatic and celiac branches of the vagus nerve versus preservation of the hepatic branch only. The primary endpoint is gastric emptying half-time of solid food at 6 months after surgery. Secondary outcomes include incidence of reflux esophagitis, quality of life scores (EORTC QLQ-C30/STO22), number and positivity rate of lymph nodes retrieved, and 3-year disease-free survival. The study will provide evidence for optimizing minimally invasive surgical strategies for early upper gastric cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Zaisheng Ye, doctoral  ·  +86 591 13950203076  ·  flyingengel@sina.com

Always discuss trial participation with your own doctor first.

Locations (1)

420 Fuma Road, Jin'an District, Fuzhou City, Fujian ProvinceFuzhou, Fujian, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07142122