Condition: Renal and Urinary Disorders · Renal Cancer · Renal Particial · Sponsor: Shao Pengfei
The detection rate of renal masses smaller than 7 cm has significantly increased in recent years. To preserve postoperative renal function to the greatest extent possible, guidelines from the European Association of Urology (EAU), the National Comprehensive Cancer Network (NCCN), and others have endorsed partial nephrectomy (PN) as the preferred treatment strategy for small renal masses. In conventional PN, it is necessary to clamp the renal artery or its branch arteries and employ a double-layer suturing technique to close the resection bed. This controls bleeding, maintains a clear surgical field, and prevents postoperative urinary leakage. The maximum safe duration of warm ischemia to avoid irreversible renal parenchymal damage remains controversial, though most studies indicate a window of 20-30 minutes. Consequently, the "off-clamp sutureless" concept has gained prominence. Its core principle is to avoid renal artery clamping and replace suturing with novel haemostatic techniques, thereby maximizing the preservation of healthy renal parenchyma. With the diversification of haemostatic material options and the widespread adoption of robotic-assisted systems, the off-clamp sutureless strategy has become technically feasible for small renal masses with low complexity . Multiple retrospective studies demonstrate that the off-clamp sutureless technique is non-inferior, offering safety and surgical outcomes comparable to conventional robot-assisted partial nephrectomy (RAPN).…
This description comes directly from the study's public registry record.
Pengfei Shao, Professor · +8613851925825 · spf032@hotmail.com
Haoqi Miao, Postgraduate · mhq@stu.njmu.edu.cn
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| The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital) | Nanjing, Jiangsu, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07141225