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Study identifier: NCT07140393 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study of HRS-4508 in Combination With Other Anti-tumor Therapy for Solid Tumor

Condition: Solid Tumor  ·  Sponsor: Jiangsu HengRui Medicine Co., Ltd.

PhasePhase 1/Phase 2
Planned participants120
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The study is being conducted to evaluate the efficacy, safety, and ORR of HRS-4508 combination with other anti tumor therapy in subjects with solid tumor ; to evaluate HRS-4508 DLT, MTD and RP2D, to evaluate the incidence and severity of adverse events (AE)/serious adverse events (SAE) (rated based on CTCAE v5.0), to evaluate ORR by researchers based on RECIST v1.1, to evaluate the pharmacokinetic (PK) characteristics of HRS-4508 SHR-1811, Capecitabine.

This description comes directly from the study's public registry record.

Talk to the study team

Jiaman Lin  ·  +86 180 0245 4915  ·  jiaman.lin@hengrui.com

Yadan Huo  ·  +86 13381110273  ·  Yadan.huo.yh3@hengrui.com

Always discuss trial participation with your own doctor first.

Locations (1)

Cancer Hospital Chinese Academy of Medical ScienceBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07140393