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Study identifier: NCT07140315 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

DK222 Study at Hopkins

Condition: Non-Small Cell Lung Cancer · Urothelial Cancer  ·  Sponsor: Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

PhasePhase 1
Planned participants6
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This Phase 1 clinical trial will test a new drug called \[18F\]DK222 in people with cancer. The goal is to see if the drug is safe, how it spreads through the body, how long it stays in the body, and how much radiation it gives off. \[18F\]DK222 is designed to attach strongly and specifically to a protein called PD-L1, which helps cancer hide from the immune system. This is a first in human study to collect preliminary safety and toxicity data of \[18F\]DK222.

This description comes directly from the study's public registry record.

Talk to the study team

Mehreen Nabi  ·  14109296586  ·  mnabi1@jh.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Johns Hopkins HospitalBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07140315