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Study identifier: NCT07139171 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study on the Role and Mechanism of Plasma Exosome microRNAs in Cognitive Impairment in First-episode Schizophrenia

Condition: Schizophrenia  ·  Sponsor: Tianjin Anding Hospital

PhaseN/A
Planned participants300
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

Schizophrenia is a severe mental illness characterised by positive symptoms, negative symptoms, and cognitive symptoms. In recent years, an increasing number of doctors and scholars have focused on cognitive symptoms; however, the mechanisms underlying cognitive impairment remain unclear. Recently, exosome research methods have provided new avenues for investigation. This study applies exosome research methods to first-episode, drug-naive schizophrenia patients to explore gene expression changes associated with cognitive impairment and gain a deeper understanding of the mechanisms underlying cognitive impairment. By integrating basic research with clinical findings, we aim to further investigate the molecular mechanisms underlying cognitive impairment in schizophrenia patients, identify potential intervention targets, and provide insights for future drug development.

This description comes directly from the study's public registry record.

Talk to the study team

Jie Li, Doctor  ·  +86-022-88188006  ·  jieli@tjmhc.com

Always discuss trial participation with your own doctor first.

Locations (1)

Tianjin Anding HospitalTianjin, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07139171