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Study identifier: NCT07138144 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy, Safety, and ToLerability of Switching to A Two-Drug Regimen With DTG/3TC Compared to Maintaining A Three-Drug REgimen With BIC/FTC/TAF or DTG/3TC/ABC in ViroLogically SupprEssed PeopLe Living With HIV After 24 and 48 Weeks of Follow-Up

Condition: HIV Infections  ·  Sponsor: José Antonio Mata Marín

PhasePhase 4
Planned participants156
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

This is a phase 4, randomized, controlled, open-label, single-center clinical trial conducted at the Hospital de Infectología, National Medical Center "La Raza." The study employs a non-inferiority design with follow-up assessments at 24 and 48 weeks. The study will enroll 156 PLWH aged ≥18 years who are on ART with BIC/FTC/TAF or DTG/3TC/ABC and have maintained virological suppression (HIV-1 RNA \<50 copies/mL) for at least 48 weeks. Participants will be randomized in a 2:1 ratio: 104 to switch to DTG/3TC and 52 to continue their current regimen (control group).

This description comes directly from the study's public registry record.

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Locations (1)

Hospital de Infectología, Centro Médico Nacional La RazaMexico City, Mexico City, MexicoRecruiting

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Source record: clinicaltrials.gov/study/NCT07138144