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Study identifier: NCT07137832 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

OPtimizing REperfusion by Intra-Arterial ThRomboLysis as Adjunct to Endovascular Treatment for Medium Vessel Occlusion

Condition: Acute Ischemic Stroke  ·  Sponsor: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

PhasePhase 3
Planned participants530
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

PEARL-MeVO is an investigator-initiated, multicenter, prospective, randomized controlled, open-label, blinded endpoint (PROBE) clinical trial aiming at evaluating the efficacy and safety of intra-arterial thrombolysis as adjunct to endovascular treatment in improving 90-day functional outcome in acute ischemic stroke patients due to medium vessel occlusion (MeVO) within 24 hours of symptom onset.

This description comes directly from the study's public registry record.

Talk to the study team

Zhenhong Deng  ·  86-20-81332619  ·  dengzhh58@mail.sysu.edu.cn

Xinguang Yang  ·  86-20-81332619  ·  yangxinguang0926@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

Sun Yat-sen Memorial Hospital, Sun Yat-sen UniversityGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07137832