Condition: Primary Aldosteronism · Hypertension · Sponsor: Third Military Medical University
The goal of this observational study is to learn about the optimal dose of spironolactone treatment and the long-term outcomes on cardiovascular and cerebrovascular events in patients with lateralized PA who are unwilling to undergo surgery. The main question it aims to answer is: 1. What is the long-term effect of spironolactone treatment for lateralized PA? 2. What is the optimal dose of spironolactone treatment for the relief of renin inhibition in patients with lateralized PA? Participants will receive spironolactone treatment as part of their regular medical care for more than 12 months, and their clinical indicators, including blood pressure, biochemical remission, cardiovascular and renal damage, and the incidence of cardiovascular and cerebrovascular events, will be analyzed.
This description comes directly from the study's public registry record.
Zhencheng Yan, MD · +8613983656682 · zhenchengyan@sina.com
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| Daping Hospital, Army Medical Center of PLA | Chongqing, Chongqing Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07137364