Condition: Renal Anemia of Chronic Kidney Disease · Sponsor: Guangdong Provincial People's Hospital
For patients with renal anemia treated with hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI), there is a clinical need of switching to long-acting and safe medications. Pegmolesatide, a polyethylene glycol (PEG)-conjugated erythropoiesis-stimulating peptide, is a long-acting erythropoiesis-stimulating agent (ESA) with sustained activity. It was approved for marketing by the National Medical Products Administration (NMPA) in June 2023. Phase III clinical trials have demonstrated its efficacy and safety in dialysis patients with renal anemia who were previously treated with recombinant human erythropoietin (rHuEPO). However, there are currently no data regarding the efficacy and safety of switching from HIF-PHIs to pegmolesatide, and there is a lack of standard for the dose conversion. This study is a multi-center, prospective, open-label, randomized parallel-controlled clinical trial, planning to enroll 96 patients. All enrolled patients will receive 12 weeks of treatment and be followed up for 16 weeks.
This description comes directly from the study's public registry record.
Xueqing Yu · +86-20-83827812 · yuxueqing@gdph.org.cn
Zhiming ye · 138 2616 1678 · yezhiming@gdph.org.cn
Always discuss trial participation with your own doctor first.
| Beijing Hospital | Beijing, Beijing Municipality, China | Not Yet Recruiting |
| Longyan First Hospital | Longyan, Fujian, China | Not Yet Recruiting |
| Zhangzhou Municipal Hospital of Fujian Province | Zhangzhou, Fujian, China | Not Yet Recruiting |
| Guangdong Provincial People's Hospital | Guangzhou, Guangdong, China | Not Yet Recruiting |
| The First Affiliated Hospital of Guangzhou Medical University | Guangzhou, Guangdong, China | Not Yet Recruiting |
| Meizhou People's Hospital | Meizhou, Guangdong, China | Not Yet Recruiting |
| The First Affiliated Hospital of Shantou University Medical College | Shantou, Guangdong, China | Not Yet Recruiting |
| Yuebei People's Hospital | Shaoguan, Guangdong, China | Not Yet Recruiting |
| Zhongshan Hospital of Traditional Chinese Medicine | Zhongshan, Guangdong, China | Not Yet Recruiting |
| Affiliated Hospital of Zunyi Medical University | Zunyi, Guizhou, China | Not Yet Recruiting |
| Jingmen Central Hospital | Jingmen, Hubei, China | Not Yet Recruiting |
| CNPG Dongfeng General Hospital | Shiyan, Hubei, China | Not Yet Recruiting |
+ 12 more locations — full list on the registry record.
Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.
We email about this public record only. Unsubscribe anytime with one click. Never medical advice.
This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07136792