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Study identifier: NCT07136779 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

First-in-Human Trial of VBC101 in Participants With Advanced Solid Tumor Malignancies

Condition: Participants With Advanced Solid Tumor Malignancies  ·  Sponsor: VelaVigo Bio Inc

PhasePhase 1/Phase 2
Planned participants310
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, open-label, multiple-dose, FIH Phase 1/2a trial. The Phase 1 portion adopts an accelerated titration for the first dose level, followed by BOIN design to identify the MTD and/or RP2D with potential backfill cohorts. The Phase 2a portion consists of dose optimization followed by cohort expansion to confirm safety and tolerability and to further evaluate the efficacy of the selected RP2D in selected solid tumor malignancies for VBC101.

This description comes directly from the study's public registry record.

Talk to the study team

Chen Li  ·  +86 13681943496  ·  chen.li@velavigo.com

Always discuss trial participation with your own doctor first.

Locations (5)

Start MidwestGrand Rapids, Michigan, United StatesRecruiting
The University of Texas MD Anderson Cancer CenterHouston, Texas, United StatesRecruiting
NEXT OncologySan Antonio, Texas, United StatesRecruiting
START Mountain Region, LLC.West Valley City, Utah, United StatesRecruiting
NEXT VirginiaFairfax, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07136779