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Study identifier: NCT07136012 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

OCEAN(a)-PreEvent - Olpasiran Trials of Cardiovascular Events And LipoproteiN(a) Reduction to Prevent First Major Cardiovascular Events

Condition: Cardiovascular Disease  ·  Sponsor: Amgen

PhasePhase 3
Planned participants11000
Who can joinAll sexes, 50 Years to 105 Years
Healthy volunteersNo

About this study

The primary objective is to evaluate the effect of olpasiran, compared to placebo, on the risk for coronary heart disease death (CHD death), myocardial infarction, or urgent coronary revascularization in participants at risk for a first major cardiovascular event with elevated lipoprotein(a) (Lp\[a\]).

This description comes directly from the study's public registry record.

Talk to the study team

Amgen Call Center  ·  866-572-6436  ·  medinfo@amgen.com

Always discuss trial participation with your own doctor first.

Locations (249)

Advanced Cardiovascular LLCAlexander City, Alabama, United StatesRecruiting
University of Alabama Birmingham Saint Vincents BirminghamBirmingham, Alabama, United StatesRecruiting
Birmingham Clinical ResearchBirmingham, Alabama, United StatesRecruiting
Alliance For Multispecialty Research - DaphneDaphne, Alabama, United StatesRecruiting
Eastern Shore Research InstituteFairhope, Alabama, United StatesRecruiting
Heart Center Research LLCHuntsville, Alabama, United StatesRecruiting
CB Flock Research CorporationMobile, Alabama, United StatesRecruiting
Phoenix ClinicalPhoenix, Arizona, United StatesRecruiting
Elite Clinical Studies LLCPhoenix, Arizona, United StatesRecruiting
Hero Clinical ResearchPhoenix, Arizona, United StatesRecruiting
HonorHealth Research InstituteScottsdale, Arizona, United StatesRecruiting
Eclipse Clinical ResearchTucson, Arizona, United StatesRecruiting

+ 237 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07136012