← Eichor
Study identifier: NCT07133750 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

PM8002 (BNT327) in Combination With Chemotherapy in Patients With Metastatic Colorectal Cancer

Condition: CRC (Colorectal Cancer)  ·  Sponsor: Biotheus Inc.

PhasePhase 2
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

PM8002 (BNT327) is a bispecific antibody targeting PD-L1 and VEGF. This is a phase II trial to evaluate the efficacy and safety of PM8002 in combination with chemotherapy in first line MSS or MSI-L/pMMR metastatic colorectal cancer.

This description comes directly from the study's public registry record.

Talk to the study team

Xuelian Xing  ·  +86 18310237570  ·  xuelian.xing@biontech.com

Always discuss trial participation with your own doctor first.

Locations (11)

Peking University First HospitalBeijing, Beijing Municipality, ChinaRecruiting
Sun Yat-sen University Cancer CenterGuangzhou, Guangdong, ChinaRecruiting
Guangdong Provincial People's HospitalGuangzhou, Guangdong, ChinaRecruiting
Harbin Medical University Cancer HospitalHarbin, Heilongjiang, ChinaRecruiting
Hubei Cancer HospitalWuhan, Hubei, ChinaRecruiting
Jilin Cancer HospitalChangchun, Jilin, ChinaRecruiting
Cancer Hospital of Shandong First Medical UniversityJinan, Shandong, ChinaRecruiting
Fudan University Shanghai Cancer CenterShanghai, Shanghai Municipality, ChinaRecruiting
Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of MedicineShanghai, Shanghai Municipality, ChinaRecruiting
Sichuan Cancer HospitalChengdu, Sichuan, ChinaRecruiting
Zhejiang Cancer HospitalHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07133750