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Study identifier: NCT07130786 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

Condition: Seizures · Primary Motor Cortex · Brain Metastases From Non-small Cell Lung Cancer (NSCLC)  ·  Sponsor: Ayal A. Aizer, MD

PhasePhase 2
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a randomized trial for patients with brain metastases in the primary motor cortex who have not had seizures to receive either the prophylactic anti-seizure medication levetiracetam (also known by its trade name Keppra) or proceed with standard of care management, which does not currently include prophylactic levetiracetam. Patients who enroll to this trial will be randomized to receive prophylactic levetiracetam or not receive prophylactic levetiracetam.

This description comes directly from the study's public registry record.

Talk to the study team

Ayal A Aizer, MD, MHS  ·  (617) 732-7560  ·  aaaizer@partners.org

Ivy B Ricca, BA  ·  (617) 582-8927  ·  iricca@mgb.org

Always discuss trial participation with your own doctor first.

Locations (1)

Brigham and Women's HospitalBoston, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07130786