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Study identifier: NCT07130357 Synced from ClinicalTrials.gov · July 29, 2026
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The Effect of Collagen Scaffold Augmentation in Achilles Tendon Rupture Repair

Condition: Achilles Tendon Rupture  ·  Sponsor: Chinese University of Hong Kong

PhaseNA
Planned participants48
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This prospective multicenter randomized controlled trial evaluates the clinical efficacy of collagen scaffold augmentation in surgical repair for acute Achilles tendon ruptures. The study will enroll 48 adult participants randomly assigned to either the intervention group (surgical repair with collagen scaffold augmentation) or the control group (standard surgical repair without scaffold). The primary outcome is tendon function assessed using the VISA-A score, while secondary outcomes include tendon healing characteristics measured by ultrasound (thickness, neovascularity), calf muscle strength, ankle range of motion, and complication rates. Follow-up assessments will be conducted at 6 weeks, 3 months, 6 months, and 12 months post-surgery. The study aims to determine whether collagen scaffold augmentation enhances tendon healing and functional recovery compared to conventional repair methods, potentially offering a improved treatment approach for Achilles tendon injuries.

This description comes directly from the study's public registry record.

Talk to the study team

Samuel K Ling, MBChB (CUHK), ChM (Edin), MRCS  ·  +852 3505-2010  ·  samuel.ling@link.cuhk.edu.hk

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Locations (1)

Prince of Wales HospitalShatin, New Territories, Hong KongRecruiting

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Source record: clinicaltrials.gov/study/NCT07130357