Condition: Graves Disease · Sponsor: Shanghai Zhongshan Hospital
Graves' disease is an autoimmune disease. The TSH receptor antibody(TRab) produced by B cells drives the production of thyroid hormone, which causes systemic disorders and thyroid eye disease. The purpose of this study is to investigate the efficacy and safety of allogeneic anti-CD19 CAR-T for refractory Graves' disease. The participants with refractory Graves' disease will receive a single dose of allogeneic anti-CD19 CAR-T and be regularly seen for the change of serum TRab, FT3, FT4 and clinical presentations, as well as any adverse events.
This description comes directly from the study's public registry record.
Jingjing JIANG, MD, PhD · 86-021-64041990 · jiang.jingjing@zs-hospital.sh.cn
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| Zhongshan Hospital Fudan University | Shanghai, Shanghai Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07129642