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Study identifier: NCT07127471 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Computer-Aided Water Exchange Colonoscopy With and Without Linked-Color Imaging for Detection of Clinically Significant Serrated Lesions

Condition: Sessile Colonic Polyp · Serrated Lesion · Sessile Serrated Lesion  ·  Sponsor: Evergreen General Hospital, Taiwan

PhaseNA
Planned participants1090
Who can joinAll sexes, 40 Years to 80 Years
Healthy volunteersYes

About this study

The goal of this clinical trial is to compare the detection rate of clinically significant serrated lesions (CSSL) in participants undergoing water exchange (WE) colonoscopy with artificial intelligence (AI)-based computer-aided detection (CADe) for screening, surveillance, diagnosis for symptoms, or referred owing to a positive fecal immunochemical test (FIT) or guaiac fecal occult blood test (gFOBT) result. There will be two arms in this study: WE with AI-assisted CADe (WEAID) control and WEAID plus linked-color imaging (LCI). The main question it aims to answer is whether the addition of LCI into WEAID colonoscopy increases CSSL detection rate. Both groups use water instead of air to insert the colonoscope into the cecum. The control method uses CADe to help detect colonic lesions. The study method uses a combination of CADe and LCI to detect lesions. Researchers will compare CSSL detection rate to see if the addition of LCI increases the detection of CSSL during CADe-assisted WE colonoscopy.

This description comes directly from the study's public registry record.

Talk to the study team

Chi-Liang Cheng, MD  ·  +886 919 768058  ·  chiliang.cheng@gmail.com

Rungsun Rerknimitr, MD  ·  +66 81 902 6633  ·  ERCP@live.com

Always discuss trial participation with your own doctor first.

Locations (4)

University of Montreal Medical Center (CHUM)Montreal, Quebec, CanadaNot Yet Recruiting
Ospedale ValduceComo, ItalyNot Yet Recruiting
Evergreen General HospitalTaoyuan, TaiwanRecruiting
King Chulalongkorn Memorial HospitalBangkok, ThailandNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07127471