Condition: Upper Tract Urothelial Carcinoma · Neoadjuvant Therapy · PD-1 Inhibitor · Sponsor: Tianjin Medical University Second Hospital
This study is designed as an open-label, single-arm, single center, phase II clinical trial, aiming to evaluate the efficacy of neoadjuvant Tislelizumab combined with Nab-Paclitaxel for patients with non-metastatic upper tract urothelial carcinoma (UTC). Patients enrolled will receive 2-3 cycles of Tislelizumab in combination with Nab-Paclitaxel every 3 weeks and then undergo radical nephroureterectomy (RNU). The assessment of efficacy is based on the histology of specimen from RNU, and treatment-related adverse events (TRAEs) will be recorded and evaluated according to CTCAE 5.0.
This description comes directly from the study's public registry record.
Hailong Hu · +86 13662096232 · Huhailong@tmu.edu.cn
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| The Second Hospital of Tianjin Medical University | Tianjin, Outside U.S., China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07126119