Condition: Ureteral Cancer · Neoadjuvant Therapy · PD-1 Inhibitor · Sponsor: Tianjin Medical University Second Hospital
This study is designed as an open-label, single-arm, single-center, phase II clinical trial, aiming to evaluate the efficacy and safety of neoadjuvant Tislelizumab combined with Nab-Paclitaxel followed by distal ureterectomy for patients with non-metastatic ureteral cancer (UTC). Patients enrolled will receive 2-3 cycles of Tislelizumab in combination with Nab-Paclitaxel every 3 weeks and then undergo distal ureterectomy (DU). The assessment of efficacy is based on the histology of specimen from DU, and treatment-related adverse events (TRAEs) will be recorded and evaluated according to CTCAE 5.0.
This description comes directly from the study's public registry record.
Hailong Hu, PhD · +86 13662096232 · Huhailong@tmu.edu.cn
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| The Second Hospital of Tianjin Medical University | Tianjin, Outside U.S., China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07125547