Condition: Chronic Primary Orofacial Pain (CPOP) · Persistent Idiopathic Facial Pain (PIFP) · Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Use these resources to provide understandable information about this study to patients, families, and health care providers: The present randomized clinical trial (RCT), conducted at the IRCCS Carlo Besta Neurological Institute, aims to evaluate the effectiveness of Pain Reprocessing Therapy (PRT), a form of psychological support/psychotherapy based on cognitive-behavioral therapy, which has already proven effective in the treatment of other types of primary chronic pain. Chronic Primary Orofacial Pain (CPOP) is a rare and complex form of chronic pain that predominantly affects adult women and occurs without evident lesions, yet has a significant emotional and functional impact. It was recently classified among chronic primary pain conditions in the ICD-11 and is considered a form of nociplastic pain, associated with alterations in brain connectivity. At present, pharmacological treatments have shown limited effectiveness. This randomized clinical trial (RCT), conducted at the IRCCS Carlo Besta Neurological Institute, aims to evaluate the effectiveness of Pain Reprocessing Therapy (PRT), a form of psychological support/psychotherapy based on cognitive-behavioral therapy, which has already proven effective in the treatment of other types of primary chronic pain. Sixty participants, all diagnosed with CPOP according to ICD-11 criteria, will be selected and randomly assigned to two groups: one will receive PRT, the other will receive treatment as usual (TAU). The primary ou…
This description comes directly from the study's public registry record.
Licia Grazzi, MD · + 39 02.2394 · licia.grazzi@istituto-besta.it
Alessandra Telesca, phd · alessandra.telesca@istituto-besta.it
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| Fondazione IRCCS Istituto Neurologico Carlo Besta | Milan, Italy | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07123233