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Study identifier: NCT07123207 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Preliminary Clinical Study on the Effect of Bacillus Subtilis on the Efficacy of Infliximab in Patients With Crohn's Disease

Condition: Mild to Severe Crohns Disease  ·  Sponsor: The Third Xiangya Hospital of Central South University

PhaseNA
Planned participants24
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to evaluate the effect of supplementing Bacillus subtilis compared to the control group on the efficacy of Infliximab in patients with Crohn's disease, and to summarize the role of supplementing Bacillus subtilis in the treatment of CD patients. Participants will be randomized into two groups: the Bacillus subtilis supplementation group and the control group. The patients in the Bacillus subtilis supplementation group received oral Bacillus subtilis capsules for 12 weeks. The control group did not receive additional intervention. Follow up once a week, and after the study, patients will come to the hospital to finish the evaluation indicators.

This description comes directly from the study's public registry record.

Talk to the study team

Xiaoyan Wang, MD  ·  +8613974889301  ·  wangxiaoyan@csu.edu.cn

Jie Hong, PHD  ·  +8613585691936  ·  jiehong97@sjtu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

The Third Xiangya Hospital of Central South UniversityChangsha, Hunan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07123207