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Study identifier: NCT07122453 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Safety and PK of Intrathecal CNTX-3001 for Intractable Chronic Low Back Pain

Condition: Lower Back Pain  ·  Sponsor: Centrexion Therapeutics

PhasePhase 1
Planned participants16
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This clinical study is being conducted to evaluate the safety, tolerability, plasma pharmacokinetics and efficacy of an investigational drug called CNTX-3001. This Phase 1 study is the first time that CNTX-3001 will be given to people (first-in-human study). The study is being done to evaluate whether CNTX-3001, given into the intrathecal space by lumbar puncture, can be administered safely to participants who have been diagnosed with intractable chronic moderate to severe low back pain and who have not responded well to other treatments in the past. CNTX-3001 is a novel, non-opioid small molecule

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Operations  ·  (617) 837-6911  ·  clinicalops@centrexion.com

Always discuss trial participation with your own doctor first.

Locations (1)

NeurovationsNapa, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07122453