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Study identifier: NCT07120971 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Metformin for Premature Infants With Bronchopulmonary Dysplasia

Condition: Bronchopulmonary Dysplasia (BPD)  ·  Sponsor: Medical College of Wisconsin

PhaseEARLY_Phase 1
Planned participants40
Who can joinAll sexes, 7 Days to 6 Months
Healthy volunteersNo

About this study

The overall objective of this study is to investigate the role of metformin in decreasing lung injury and promoting lung growth in premature infants. There are two phases to this pilot study. For Phase 0, the goal is to investigate the safety and tolerance of oral metformin in premature who have been diagnosed with bronchopulmonary dysplasia (BPD) at 36-44 weeks gestation. For Phase 1, the goal is to investigate metformin safety and tolerance in extremely premature infants who are 7-30 days old who have an increased risk of BPD. The main questions it aims to answer are: * how well do older premature infants tolerate metformin? * how well do younger premature infants tolerate metformin?

This description comes directly from the study's public registry record.

Talk to the study team

Kathleen Meskin, BSN, RN, CCRP  ·  414-337-7171  ·  kmeskin@mcw.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Children's WisconsinMilwaukee, Wisconsin, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07120971