Condition: Cocaine Use Disorder · Sponsor: Hôpital le Vinatier
This study investigates how cocaine use and withdrawal affect sleep and circadian rhythms in individuals undergoing inpatient detoxification. Using wearable sleep monitors, actigraphy, questionnaires, and hormonal biomarkers, it aims to capture both objective and subjective changes in sleep across three key stages: active use, early withdrawal, and late withdrawal. The study is unique in its ability to explore sleep microstructure, the circadian system's role via melatonin and cortisol measurements, and the dynamic relationship between subjective sleep perception and objective sleep data. It also examines whether sleep quality may serve as a predictive marker of long-term withdrawal success.
This description comes directly from the study's public registry record.
ILONA MEDIGUE, PhD student · 00334 37 91 55 65 · ilona.medigue@ch-le-vinatier.fr
VERONIQUE VIAL, PM · 00334 37 91 55 22 · veronique.vial@ch-le-vinatier.fr
Always discuss trial participation with your own doctor first.
| Centre Hospitalier Le Vinatier | Bron, AURA, France | Not Yet Recruiting |
| Centre Hospitalier Le Vinatier | Bron, Auvergne-Rhône-Alpes, France | Recruiting |
| CH Le Vinatier | Bron, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07119567