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Study identifier: NCT07118956 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Respiratory-gated Transcutaneous Auricular Vagus Nerve Stimulation for Improving Apathy in Parkinson's Disease

Condition: Parkinson Disease · Apathy · Non-motor Symptoms  ·  Sponsor: Anhui Medical University

PhaseNA
Planned participants60
Who can joinAll sexes, 40 Years to 90 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn whether 100HZ respiratory-gated vagus nerve stimulation (RAVANS) can improve the non-motor symptoms in people with Parkinson's disease (PD). It will also learn the safety of 100HZ RAVANS. The main questions it aims to answer are: Can 100HZ RAVANS improve apathy in people with PD? Did the participants have any side effects or safety issues when undergoing 100HZ RAVANS? Researchers compared 100HZ RAVANS with sham stimulation (low-dose stimulation of the same site and treatment parameters) to see if 100HZ RAVANS could improve non-motor symptoms in patients with PD. Participants will: Receive 100HZ RAVANS or sham stimulation for 2 weeks. Neuropsychological assessment, imaging and biological sample collection were conducted before and after the entire cycle.

This description comes directly from the study's public registry record.

Talk to the study team

Rong Ye, Ph.D.  ·  +8615656050129  ·  ronye.uk@gmail.com

Panpan Hu, Ph.D.  ·  +8655162923704  ·  hpppanda9@126.com

Always discuss trial participation with your own doctor first.

Locations (1)

Cognitive Neuropsychology Lab Anhui Medical UniversityHefei, Anhui, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07118956