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Study identifier: NCT07118254 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A PHASE II PROSPECTIVE RANDOMIZED DOUBLE-MASKED CROSSOVER STUDY ASSESSING THE SAFETY & EFFICACY OF RHPRG4 (450 μG/ML RECOMBINANT HUMAN PROTEOGLYCAN 4) COMPARED TO VEHICLE FOR THE TREATMENT OF OCULAR GRAFT-VERSUS-HOST DISEASE (OGVHD)

Condition: Ocular Graft Versus Host Disease  ·  Sponsor: Lubris Bio Pty Ltd

PhasePhase 2
Planned participants15
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

An 84-day, prospective, randomized (1:1) vehicle controlled, double-masked pre-market, crossover study. Subjects with moderate to severe oGVHD related Dry Eye Disease Each subject will receive both treatments in random sequence, each for 28 days, separated by a 14-day vehicle washout period.

This description comes directly from the study's public registry record.

Talk to the study team

Edward CEO  ·  6193394016  ·  ertruitt@lubris.net

Always discuss trial participation with your own doctor first.

Locations (3)

Sydney Eye HospitalSydney, New South Wales, AustraliaNot Yet Recruiting
OTABrisbane, Queensland, AustraliaRecruiting
Royal Melbourne HospitalMelbourne, Victoria, AustraliaRecruiting

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Source record: clinicaltrials.gov/study/NCT07118254