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Study identifier: NCT07115745 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Healthy Donor CD19-targeted Allogeneic CAR T Cells in Participants With Severe, Refractory Autoimmune Diseases

Condition: Refractory Autoimmune Diseases  ·  Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company

PhasePhase 1
Planned participants125
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to determine the safety, tolerability, optimal dose, and preliminary efficacy of BMS-986515, a healthy donor (HD) allogeneic CD19-targeted CART cell product, in participants with severe, refractory autoimmune diseases.

This description comes directly from the study's public registry record.

Talk to the study team

BMS Clinical Trials Contact Center www.BMSClinicalTrials.com  ·  855-907-3286  ·  Clinical.Trials@bms.com

First line of the email MUST contain NCT # and Site #.

Always discuss trial participation with your own doctor first.

Locations (28)

Brigham And Womens HospitalBoston, Massachusetts, United StatesRecruiting
Duke UniversityDurham, North Carolina, United StatesRecruiting
Local Institution - 0007Camperdown, New South Wales, AustraliaWithdrawn
Local Institution - 0008Brisbane, Queensland, AustraliaWithdrawn
Local Institution - 0013Clayton, Victoria, AustraliaWithdrawn
Local Institution - 0040Salvador, Estado de Bahia, BrazilNot Yet Recruiting
Local Institution - 0039Porto Alegre, BrazilNot Yet Recruiting
Local Institution - 0038São Paulo, BrazilNot Yet Recruiting
Local Institution - 0004Prague, Praha 5, CzechiaNot Yet Recruiting
Revmatologicky ustavPrague, CzechiaRecruiting
CHU Strasbourg-HautepierreStrasbourg, Alsace, FranceRecruiting
Hopital Claude Huriez - CHU de LilleLille, Nord, FranceRecruiting

+ 16 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07115745