Condition: Breast Neoplasms · Colorectal Neoplasms · Prostate Neoplasm · Sponsor: Eli Lilly and Company
The main purpose of this study is to evaluate safety, tolerability, and efficacy of LY4257496 alone and as part of relevant standard of care (SOC) combination therapy in participants with Gastrin-releasing Peptide Receptor (GRPR)-positive advanced cancer, including but not limited to breast, colorectal, prostate, endometrial, esophageal, gastroesophageal (GE) junction, and gastric cancer. The study will also evaluate the safety, tolerability, and efficacy of LY4257529 to identify cancer with high levels of a protein called GRPR. This is a 2-part study. Participation could last up to 36 weeks or until your tumor progresses.
This description comes directly from the study's public registry record.
Trial questions or participation questions: 1-877-CTLILLY (1-877-285-4559) or · 1-317-615-4559 · LillyTrials@Lilly.com
Physicians interested in becoming principal investigators please contact · clinical_inquiry_hub@lilly.com
Always discuss trial participation with your own doctor first.
| City of Hope | Duarte, California, United States | Recruiting |
| University of California, Los Angeles (UCLA) | Santa Monica, California, United States | Recruiting |
| Stanford University Medical Center | Stanford, California, United States | Recruiting |
| Biogenix Molecular, LLC | Miami, Florida, United States | Recruiting |
| Moffitt | Tampa, Florida, United States | Recruiting |
| Emory University School of Medicine - Winship Cancer Institute | Atlanta, Georgia, United States | Recruiting |
| Massachusetts General Hospital | Boston, Massachusetts, United States | Not Yet Recruiting |
| Dana-Farber Cancer Institute | Boston, Massachusetts, United States | Not Yet Recruiting |
| Barbara Ann Karmanos Cancer Institute | Detroit, Michigan, United States | Recruiting |
| BAMF Health Inc. | Grand Rapids, Michigan, United States | Recruiting |
| Washington University | St Louis, Missouri, United States | Recruiting |
| New York University (NYU) Langone Medical Center | New York, New York, United States | Not Yet Recruiting |
+ 19 more locations — full list on the registry record.
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This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.
Source record: clinicaltrials.gov/study/NCT07114601