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Study identifier: NCT07113769 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Plasma Biomarkers and Platelet Morphology of Extracorporeal CardioPulmonary Resuscitation

Condition: ExtraCorporeal Membrane Oxygenation (ECMO) · Cardiac Arrest  ·  Sponsor: Central China Fuwai Hospital of Zhengzhou University

PhaseN/A
Planned participants130
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Extracorporeal cardiopulmonary resuscitation (ECPR) constitutes a pivotal emergency intervention for cardiac arrest (CA) patients. However, current eligibility criteria and prognostic assessment metrics remain substantially limited, relying predominantly on clinical symptoms and physical signs while lacking objective biomarker data. Integrating reproducible, highly sensitive, and specific proteinaceous and metabolic indicators with ultrastructural platelet alterations may hold significant implications for both ECPR administration and prognostication in CA. Therefore, the purpose of this study is to identify the plasma proteomic and metabolomic characteristics of patients with refractory cardiac arrest before and after ECPR treatment, as well as the characteristics of platelet morphological and structural changes, to search for potential specific markers that can predict CA patients who may benefit from ECPR so as to optimize treatment selection.

This description comes directly from the study's public registry record.

Talk to the study team

Jianchao Li  ·  +86 185 3998 9191  ·  381226651@qq.com

Always discuss trial participation with your own doctor first.

Locations (1)

Fuwai Central China Cardiovascular HospitalZhengzhou, Henan, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07113769