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Study identifier: NCT07112378 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

Condition: Eosinophilic Esophagitis (EoE)  ·  Sponsor: Regeneron Pharmaceuticals

PhasePhase 3
Planned participants20
Who can joinAll sexes, 6 Months to 6 Years
Healthy volunteersNo

About this study

This study is researching an experimental drug called dupilumab (called "study drug"). The study is focused on children with active eosinophilic esophagitis (EoE; an inflammatory disease of the esophagus) which impacts feeding and nourishment. The aim of the study is to see how safe, tolerable, and effective the study drug is when given for 24 weeks to children with active EoE. The study is looking at several other research questions, including: * What side effects may happen from taking the study drug * How much study drug is in the blood at different times * Whether the body makes antibodies against the study drug (which could make the drug less effective or could lead to side effects)

This description comes directly from the study's public registry record.

Talk to the study team

Clinical Trials Administrator  ·  844-734-6643  ·  clinicaltrials@regeneron.com

Always discuss trial participation with your own doctor first.

Locations (11)

Phoenix Childrens HospitalPhoenix, Arizona, United StatesRecruiting
University of California San Francisco (UCSF)San Francisco, California, United StatesRecruiting
Children's Hospital ColoradoAurora, Colorado, United StatesRecruiting
GI Care for Kids LLCAtlanta, Georgia, United StatesRecruiting
Massachusetts General HospitalBoston, Massachusetts, United StatesRecruiting
Weill Cornell MedicineNew York, New York, United StatesRecruiting
University of North Carolina, Bioinformatics BuildingChapel Hill, North Carolina, United StatesRecruiting
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania, United StatesRecruiting
Medical University of South CarolinaCharleston, South Carolina, United StatesRecruiting
Cook Children's Medical CenterFort Worth, Texas, United StatesRecruiting
University of VirginiaCharlottesville, Virginia, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07112378