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Study identifier: NCT07112365 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

The FINTEPLA as an Anti-SUDEP Therapy in Dravet Syndrome Project

Condition: Dravet Syndrome  ·  Sponsor: The University of Texas Health Science Center, Houston

PhasePhase 4
Planned participants25
Who can joinAll sexes, 16 Years to no upper limit
Healthy volunteersNo

About this study

This study investigates cerebrovascular reactivity (CVR) and functional brain connectivity in Dravet Syndrome (DS) patients with convulsive seizures. Using functional MRI (fMRI), we will define differences in brain responses to CO₂ changes before administration of the drug Fintepla (Baseline), with a library of healthy controls and with those obtained after administration of Fintepla (Day \~60). Changes in CVR and their relation to ventilatory responses will also be assessed during fMRI.

This description comes directly from the study's public registry record.

Talk to the study team

Samden Lhatoo, MD, FRCP  ·  (713) 500-7106  ·  Samden.D.Lhatoo@uth.tmc.edu

Sandhya Rani  ·  (713) 500-7499  ·  M.R.Sandhya.Rani@uth.tmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The University of Texas Health Science Center at HoustonHouston, Texas, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07112365