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Study identifier: NCT07110129 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Using sEMG of the Diaphragm to Assess Readiness for Extubation

Condition: Critical Illness  ·  Sponsor: Cardiff and Vale University Health Board

PhaseN/A
Planned participants30
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

As part of an admission to an Intensive Care Unit (ICU) many patients have breathing tube inserted into their windpipe, also referred to as intubation . This is done for a variety of reasons which can include the need for invasive breathing support and to place the patient into a medically induced coma to allow their body to rest and be treated for the underlying cause of their deterioration. One the patient has started to recover from their illness, the process of removing the breathing tube (extubation) and stopping the breathing machine begins. Optimising this process and ensuring successful removal of the breathing tube is extremely important to optimise outcomes. Therefore, identifying new methods to determine the likelihood for successful extubation is of clinical significance. There are several markers of extubation readiness that clinicians can use to support their decision making discussed in the literature. A novel method is the use of respiratory muscle activity monitoring via sensory electromyogram (sEMG). sEMG has previously been shown to be useful to measure the strength and activity of muscles. However, until recently measuring diaphragm activity has been a challenge due to noise from the chest movements, cardiac artefacts. Recent advancements in signal processing and growing interest in better diagnostic methods has led to an improvement in metrics. Using wavelet transforms and machine learning, new techniques have been developed to measure diaphragm muscle …

This description comes directly from the study's public registry record.

Talk to the study team

Paul Twose, PhD  ·  +447739315830  ·  paul.twose@wales.nhs.uk

Always discuss trial participation with your own doctor first.

Locations (1)

Cardiff and Vale University Health BoardCardiff, United KingdomRecruiting

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Source record: clinicaltrials.gov/study/NCT07110129