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Study identifier: NCT07110038 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

DEPECA-1 - A Phase II Study to Evaluate a First-line Systemic Therapy With Enfortumab Vedotin Plus Avelumab for Advanced and Metastatic Penile Carcinoma

Condition: Penile Squamous Cell Carcinoma (PSCC)  ·  Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest

PhasePhase 2
Planned participants25
Who can joinMale, 18 Years to no upper limit
Healthy volunteersNo

About this study

The DEPECA-1 trial is the first systematic Phase II trial to evaluate response and survival to a combination of antibody-drug conjugate enfortumab vedotin plus the PD-L1 inhibitor avelumab in patients with locally advanced and metastatic penile squamous cell carcinoma (PeCa) in the 1st line setting.

This description comes directly from the study's public registry record.

Talk to the study team

Igor Tsaur, Prof. Dr.  ·  +49 7071-29-86000  ·  igor.tsaur@med.uni-tuebingen.de

Claudia Pauligk, Dr.  ·  +49 69 5899 787 52  ·  depeca-1@ikf-khnw.de

Always discuss trial participation with your own doctor first.

Locations (8)

Universitätsklinikum Carl Gustav CarusDresden, GermanyRecruiting
University Hospital and Medical Faculty, Heinrich-Heine-University, DüsseldorfDüsseldorf, GermanyRecruiting
University Medical Center of Johannes Gutenberg-UniversityMainz, GermanyRecruiting
University Hospital MannheimMannheim, GermanyRecruiting
Technical University of Munich, University Hospital MunichMunich, GermanyRecruiting
Caritas St. Josef Medical CenterRegensburg, GermanyRecruiting
Rostock University Medical CenterRostock, GermanyRecruiting
University Hospital TübingenTübingen, GermanyRecruiting

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Source record: clinicaltrials.gov/study/NCT07110038