Condition: Heart Failure · Inspiratory Capacity · Inspiratory Muscle Strength · Sponsor: CAROLINA NIGRO DI LEONE
Introduction Exercise intolerance is the most common symptom in patients with heart failure (HF), significantly impacting their quality of life and functional capacity. Muscle metabolism may be impaired due to sympathetic hyperactivation, systemic inflammation, and neurohormonal alterations, contributing to ventilatory inefficiency and exercise intolerance. Inspiratory muscle training (IMT) has been shown to improve inspiratory muscle strength and endurance, reducing fatigue and the sensation of dyspnea. There is a gap in the evidence regarding the use of IMT in hospitalized settings, particularly concerning short-term gains in inspiratory muscle strength and the safety of the intervention. This study aims to evaluate the effects of IMT on inspiratory muscle strength, hemodynamic and functional outcomes, as well as the safety of the IMT protocol in hospitalized patients with HF. Methods A randomized, controlled clinical trial will be conducted in the Cardiac Intensive Care Unit of the University Hospital Pedro Ernesto. The study will include individuals of both sexes, aged 18 years or older, who are hospitalized due to heart failure. Exclusion criteria will include: pregnancy; head trauma and/or brain injury; motor disability; signs and/or symptoms of low cardiac output; acute coronary syndrome; advanced HF with left ventricular ejection fraction (LVEF) below 20%; presence of untreated tachyarrhythmias or bradyarrhythmias; use of high-dose inotropes or vasopressors or an i…
This description comes directly from the study's public registry record.
Carolina N DI LEONE, Master degree reseacher · +5521998043470 · caroll_nigro@hotmail.com
Luiz F Rodrigues Junior, PhD professor · 55 21 · luiz.junior@unirio.br
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| Carolina Nigro Di Leone | Rio de Janeiro, Rio de Janeiro, Brazil | Not Yet Recruiting |
| Pedro Ernesto University Hospital | Rio de Janeiro, Rio de Janeiro, Brazil | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07108231