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Study identifier: NCT07107945 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

A Study to Find Out How EMPAgliflozin is Tolerated and if it Helps Children and Adolescents With Chronic KIDNEY Disease (EMPA-KIDNEY® Kids)

Condition: Chronic Kidney Disease  ·  Sponsor: Boehringer Ingelheim

PhasePhase 3
Planned participants120
Who can joinAll sexes, 2 Years to 17 Years
Healthy volunteersNo

About this study

This study is open to children aged 2 to 17 with chronic kidney disease (CKD). The purpose of this study is to find out if a medicine called empagliflozin helps children and adolescents with CKD. Other goals of the study are to find out how empagliflozin is tolerated and handled by the body in children and adolescents with CKD. Participants are put into 2 groups randomly, which means by chance. One group takes empagliflozin and the other group takes placebo. Placebo looks like empagliflozin but does not contain any medicine. Participants are twice as likely to be in the empagliflozin group. Participants take empagliflozin or placebo as tablets once a day for 6 months. After 6 months, participants in both groups take empagliflozin as tablets once a day for 1 year. Participants are in the study for a little over a year and a half. During this time, they visit the study site about 15 times and get at least 5 phone or video calls from the site staff. At the visits, the doctors take blood and urine samples from the participants. The doctors also regularly check participants' health and take note of any unwanted effects.

This description comes directly from the study's public registry record.

Talk to the study team

Boehringer Ingelheim  ·  1-800-243-0127  ·  clintriage.rdg@boehringer-ingelheim.com

Always discuss trial participation with your own doctor first.

Locations (102)

University of Alabama at BirminghamBirmingham, Alabama, United StatesNot Yet Recruiting
Phoenix Children's HospitalPhoenix, Arizona, United StatesNot Yet Recruiting
University of California Los AngelesLos Angeles, California, United StatesNot Yet Recruiting
Stanford University School of MedicinePalo Alto, California, United StatesRecruiting
University of California DavisSacramento, California, United StatesNot Yet Recruiting
University of California San FranciscoSan Francisco, California, United StatesNot Yet Recruiting
University of MiamiMiami, Florida, United StatesNot Yet Recruiting
Emory UniversityAtlanta, Georgia, United StatesRecruiting
Ann & Robert H. Lurie Children's Hospital of ChicagoChicago, Illinois, United StatesRecruiting
Indiana UniversityIndianapolis, Indiana, United StatesRecruiting
Novak Center for Children's HealthLouisville, Kentucky, United StatesRecruiting
Johns Hopkins HospitalBaltimore, Maryland, United StatesRecruiting

+ 90 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07107945