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Study identifier: NCT07105345 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Exploring Efficacy of Multi-Mode Cognitive Processing Therapy (CPT) for PTSD

Condition: Posttraumatic Stress Disorder  ·  Sponsor: Far Eastern Memorial Hospital

PhaseNA
Planned participants60
Who can joinAll sexes, 20 Years to 65 Years
Healthy volunteersNo

About this study

This study is a longitudinal, multicenter, single-blind, two-arm randomized controlled trial designed to evaluate the effectiveness of Multi-Modal Cognitive Processing Therapy (MMCPT) for individuals with posttraumatic stress disorder (PTSD). Participants will be randomly assigned to either the intervention group receiving MMCPT or a control group receiving treatment-as-usual (TAU). The intervention follows the standard CPT manual developed by Resick and consists of twelve weekly 90-minute individual sessions. The primary outcomes include PTSD symptom severity assessed by the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5) and the PTSD Checklist for DSM-5 (PCL-5). Secondary outcomes include sleep quality (actigraphy, PSQI), anxiety (STAI), depression (HDRS-17), remission rate, and posttraumatic growth (PTGI). Assessments will occur at baseline, mid-treatment, post-treatment, and at 3-, 6-, 9-, and 12-month follow-ups.

This description comes directly from the study's public registry record.

Talk to the study team

Hsin-I Liu, PhD, RN  ·  +886-2-8966-7000  ·  femh91095@femh.org.tw

Pei-Chuan Wu, MD  ·  +886-2-8966-7000  ·  femh91988@femh.org.tw

Always discuss trial participation with your own doctor first.

Locations (2)

Far Eastern Memorial HospitalNew Taipei City, Banqiao District, TaiwanNot Yet Recruiting
Far Eastern Memorial HospitalNew Taipei City, Banqiao District, TaiwanRecruiting

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Source record: clinicaltrials.gov/study/NCT07105345