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Study identifier: NCT07104916 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Mindfulness-based Psilocybin Therapy for PTSD

Condition: Post Traumatic Stress Disorder · Depression - Major Depressive Disorder  ·  Sponsor: Anthony P King

PhasePhase 2
Planned participants30
Who can joinAll sexes, 21 Years to 65 Years
Healthy volunteersNo

About this study

The goal of this study is to learn how psilocybin delivered with mindfulness-based therapy may help symptoms of posttraumatic stress disorder (PTSD). This is an assessor-blinded, randomized, controlled study in participants with PTSD. The study will investigate the changes in brain activity, connectivity, and microstructural neuroplasticity assessed using EEG/EMG and multimodal MRI measures after administration of one oral dose of psilocybin, accompanied either with standard "psychological support" only; or with standard support plus Mindfulness-based Cognitive Therapy (MBCT).

This description comes directly from the study's public registry record.

Talk to the study team

Anthony King, PhD  ·  614 688-9537  ·  anthony.king@osumc.edu

Wenfei Yu, BS  ·  614 688-9537  ·  wenfei.yu@osumc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

The Ohio State University Medical CenterColumbus, Ohio, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07104916