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Study identifier: NCT07104487 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

[18F]AlF-NOTA-octreotide PET/MRI in Carotid Artery Disease

Condition: Stroke (CVA) or TIA · Carotid Artery Plaque · Atherosclerosis Cardiovascular Disease  ·  Sponsor: Universitaire Ziekenhuizen KU Leuven

PhasePhase 2
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This clinical trial aims to evaluate whether \[¹⁸F\]AlF-OC PET/MRI can characterize and quantify inflammation in carotid atherosclerotic plaques. The study will assess if tracer uptake in culprit and non-culprit carotid arteries, measured by standardized uptake values (SUV), is associated with future cerebrovascular events. Specifically, it will examine whether \[¹⁸F\]AlF-OC uptake predicts the risk of recurrent ipsilateral TIA, amaurosis fugax, stroke, or other vascular complications. Participants will undergo \[¹⁸F\]AlF-OC PET/MRI and will be followed via telephone interviews at 90 days, 1 year, and 3 years after their initial stroke or TIA.

This description comes directly from the study's public registry record.

Talk to the study team

Robin Lemmens, MD PhD  ·  +32 16 34 42 80  ·  robin.lemmens@uzleuven.be

Louise Maes, MD  ·  +32 16 34 42 80  ·  louise.maes@uzleuven.be

Always discuss trial participation with your own doctor first.

Locations (1)

UZ LeuvenLeuven, Vlaams-Brabant, BelgiumRecruiting

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Source record: clinicaltrials.gov/study/NCT07104487