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Study identifier: NCT07104123 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Substance Use in Pregnant People - Optimizing Retention in Treatment

Condition: Substance Use Disorder (SUD) · Pregnancy · Postpartum  ·  Sponsor: Washington University School of Medicine

PhaseNA
Planned participants40
Who can joinFemale, 18 Years to no upper limit
Healthy volunteersNo

About this study

Substance use during pregnancy is a leading cause of maternal morbidity and mortality in the United States, with 55-80% of postpartum patients disengaging from substance use disorder (SUD) treatment within one year of delivery. Structural and social determinants of health, including housing instability, transportation barriers, and limited childcare access, further exacerbate disparities in treatment retention. This pilot study, conducted in two specialized prenatal care clinics, evaluates the feasibility and acceptability of two integrated strategies to promote sustained engagement in recovery-oriented services during the perinatal and postpartum periods. Aim 1 implements a standardized social needs screening and referral protocol to connect patients with community-based supports. Aim 2 pilots a contingency management intervention to incentivize recovery-supportive behaviors. Findings will inform the design of a larger multi-site randomized controlled trial to evaluate the impact of these interventions on treatment retention, overdose prevention, and maternal-infant health outcomes.

This description comes directly from the study's public registry record.

Talk to the study team

Melissa M Mills, BS  ·  314-273-2279  ·  melissa.mills@wustl.edu

Jeannie C Kelly, MD, MS  ·  jckelly@wustl.edu

Always discuss trial participation with your own doctor first.

Locations (2)

University of MarylandBaltimore, Maryland, United StatesNot Yet Recruiting
Washington UniversitySt Louis, Missouri, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07104123